MTU links MTU A2Z Search MTU MTU Faculty and Staff Parents Alumni Relations MTU Athletics Degree Programs Current Students Prospective Students Biomedical Engineering at Michigan Tech Michigan Tech

Home

Undergraduate Research

Labs

Faculty & Staff

Undergraduate

Senior Design

Contact Us

 



                       

Undergraduates Assisting
to Restore Functional Lymphatics


Dr. Jeremy Goldman

A regenerated lymphatic capillary in skin is shown in the image draining interstitial fluid, indicated by the white arrow in image at left

Interstitial flow, directed from the blood capillaries to the lymphatic capillaries, clears interstitial macromolecules and excess fluid from the skin.  Disruptions of the lymphatic capillaries reduce interstitial flow and cause macromolecules and fluid to accumulate in the interstitium.  Such disruptions, which may lead to secondary lymphedema, are caused during axillary lymph node dissection in breast cancer patients. Unfortunately, secondary lymphedema remains poorly understood and lacks a cure. 


An undergraduate student, Sara Gibbs, captures 3 dimensional images of lymphatic capillaries in skin specimens with a fluorescence 'Apotome' microscope.
 The goal of Dr. Jeremy Goldman’s laboratory is to restore a functional lymphatic capillary network in regions of tissue that are deficient in functional lymphatics, such as the human axilla.  We are interested in understanding how lymphatic specific growth factors and matrix degrading proteases may work in tandem with interstitial flows to direct functional lymphatic growth by forming fluid channels in the extracellular matrix through which the lymphatic endothelial cells can migrate and organize into functional lymphatic capillaries

Jeremy Goldman, Ph.D.
Assistant Professor
PhD, Northwestern University

Email: jgoldman@mtu.edu

Office: 303 M&M Building

Telephone: 906-487-2851
Fax: 906-487-1717